Over the past 40 years, numerous scientific studies of the health effects of chaga have been published. If you are interested in learning more, or wish to evaluate its potential benefits for yourself, please click the links below.
Chaga Research Studies
Anti-Aging study
1) Effect of cryosubstance Chaga on deposition or isolation of 90Sr and on the effect of prolonged external exposure to gamma-radiation
Cancer Studies
1. Reversal of the TPA-induced inhibition of gap junctional intercellular communication by Chaga mushroom (Inonotus obliquus) extracts: effects on MAP kinases
2. Biologically Active Compounds from Aphyllophorales (Polypore) Fungi
3. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus.
4. Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus.
5. Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
6. The effect of aqueous extracts from Inonotus obliquus on the mitotic index and enzyme activities.
7. Antimitotic activity of aqueous extracts of Inonotus obliquus.
Anti fungal
1. Antifungal activity of cysteine, its effect on C-21 oxygenated lanosterol derivatives and other lipids in Inonofus obliquus, in vitro
Anti inflammatory
1. In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus. Click here to read more.
2. Ethanol Extract of Inonotus obliquus Inhibits Lipopolysaccharide-Induced Inflammation in RAW 264.7 Macrophage Cells
3. In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus
Antioxidant
1. Melanin complex of the fungus Inonotus obliquus Click here to read more.
2. Antioxidant effect of Inonotus obliquus.
Chemical Constituents of Inonotus obliquus
1. Chemical Constituents of Inonotus obliquus
Oxidative DNA Damage / Protection
1. Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.
Heart cells
1. Effects of bioglycans isolated from birch fungiinonotus obliquus on electric activity of venous sinus cells in frog heart
Immuno-stimulating
1. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus
2. Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus
3. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus.
Leukemia
1. Click here to read more.
2. Aqueous extracts of Inonotus obliquus vel. Poria obliqua in the diagnosis of leukemia’s